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Biovail Corporation (TSX, NYSE:BVF ) with its corporate headquarters in Mississauga, Ontario, Canada is a leading specialty pharmaceutical company. With revenues of  US$757 million in 2008, the Company is engaged in the formulation, clinical testing, registration, manufacture and commercialization of pharmaceutical products both directly and through partners.

Biovail operates wholly owned subsidiaries in Barbados, Canada, the United States, and Puerto Rico. More specifically:

Biovail Pharmaceuticals Canada

Biovail Pharmaceuticals Canada (BPC) is the Canadian sales and marketing division of Biovail Corporation. Since its entry into the Canadian market in 1997 (as Crystaal Corporation), BPC has established a reputation for providing quality pharmaceutical products to Canadian health care professionals.

BPC markets and distributes a select portfolio of products developed by Biovail and in-licensed from international pharmaceutical companies. The Company targets both specialist and primary-care physicians; and as a result, BPC has established itself as a leading pharmaceutical marketing and sales operation the Canadian market.

This business unit employs a 100-member sales force, which reflects a recent expansion. BPC promotes a well-respected portfolio of products to the approximately 9,400 physicians across the country that represent approximately 70% of the total prescriptions written in Biovail's target markets. Products promoted and distributed include Wellbutrin XL®Tiazac® XC, Nitoman® (acquired in September 2008), Ralivia™, Glumetza®, Zyban® and Monocor®.

BPC is committed to strong, sustained growth through increased market penetration and strategic expansion of its portfolio of products.

Contact Biovail Pharmaceuticals Canada

BTA Pharmaceuticals, Inc.

BTA Pharmaceuticals, Inc. (BTA), a wholly owned U.S. subsidiary located in Bridgewater, NJ. The subsidiary includes administrative, product distribution and related regulatory affairs functions. In addition to the products directly promoted through its strategic partners, the Company also distributes a number of branded off-patent products. These products, also known as Legacy products, include the well-known brands Cardizem® CD, Ativan®, Vaseretic®, Vasotec®, and Isordil in the United States. These products, for which market exclusivity has expired, are not actively promoted by Biovail.

Contact BTA Pharmaceuticals, Inc.

Biovail Manufacturing

Biovail Corporation operates modern, fully integrated, pharmaceutical manufacturing facilities located in Steinbach, Manitoba; Chantilly, Virginia; and Carolina, Puerto Rico.

These state-of-the-art facilities provide Biovail with the capacity to meet the current and anticipated demand for its portfolio of products, including Wellbutrin XL®, Ultram® ER, Cardizem® LA and a number of generic products that are distributed by Teva and Forest Laboratories, Inc. (Forest) in the United States, and by Novopharm Limited (a subsidiary of Teva) in Canada.

Biovail manufacturing sites incorporate the following processes, procedures and capabilities:

  • Manufacturing
  • Packaging
  • Warehousing
  • Planning / Purchasing
  • Distribution
  • Quality Assurance / Quality Control
  • Technology transfer
  • Process optimization
  • New-product launches

Biovail manufacturing sites are capable of supporting medicines using the following solid-dose drug-delivery technologies:

  • Tablets
  • Capsules
  • Orally disintegrating tablets (ODTs)
  • Taste-masked microspheres
  • Modified-release beads
  • Wax beads for modified release (oral solid dose)
  • Extended-release capsules
  • Extended-release tablets
  • Smart-coat matrix tablets
  • Controlled-release oral solid dose
  • CEFORM (fast-dissolving tablets)

STEINBACH MANUFACTURING

Biovail's main manufacturing facility in Steinbach, Manitoba facility totals approximately 250,000 square feet, In February 2005, Biovail announced a $27.6-million expansion project to further enhance the manufacturing capability of the facility. The addition of 60,000 square feet favorably impacted all areas of the site, including manufacturing, packaging, warehouse, laboratory operations and office space. This expansion project, which was completed in early 2007, is the third such enhancement of the facility since 2001.

PUERTO RICO MANUFACTURING

Today, Biovail operates a single manufacturing facility in Puerto Rico that totals 35,000 square feet, including 25,000 square feet of manufacturing capacity and 10,000 square feet of additional leased warehouse space. This plant is specially constructed for the high volume production of controlled-release beads. 

All Biovail manufacturing facilities meet United States Food and Drug Administration-mandated and Therapeutic Products Directorate (Canada)-mandated good manufacturing practices (GMP and cGMP), and are inspected on a regular basis by these regulatory authorities. Biovail's internal auditing team monitors compliance on an ongoing basis with such standards.

Contact Biovail Manufacturing

BIOVAIL LABORATORIES INTERNATIONAL SRL

Located in Christ Church, Barbados, Biovail Laboratories International SRL, holds the intellectual property that underlies Biovail’s products. It performs all of the activities that are involved with owning and exploiting a substantial intellectual property portfolio. For example, Biovail Laboratories International SRL develops, manufactures, and sells Biovail’s pharmaceutical products; it licenses its intellectual property; and it performs strategic planning and decision-making.

Contact Biovail Laboratories International SRL

BIOVAIL Ireland Office

Biovail Technologies (Ireland) Ltd
2010 Orchard Avenue
Citywest Business Campus
Dublin 24, Ireland
Ph.  353 1 466 1693
Fax 353 1 466 1694



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